Ryanair fares and additional services will now appear in the Sabre global distribution system following an agreement between the two companies.
The deal completes Ryanair's return to the GDS table which started with an agreement with Travelport revealed last March, followed by Amadeus in September and now Sabre.
The agreements came after a 10-year absence from third-party distribution systems for the carrier which made no secret of its preference for direct online distribution in the past.
A statement from Ryanair says the deal will allow it to continue to expand its business travel offering with the airline introducing its Business Plus service last year as well as a corporate and group arm.
The airline says 27% of its passengers are travelling for business.
The developments are also part of the airline's 'Always Getting Better' initiative which aims to improve customer service and most recently saw Ryanair sign a deal with Adobe to improve its digital marketing capabilities.
The airline is planning a new website with personalised home pages for launch in the autumn as well as a ‘hold the fare’ feature, a fare comparison tool and a new mobile app.