Expedia is running the travel search and booking functionality on six of Yahoo's travel major portals across Europe, edging out previous metasearch partner Kelkoo.
The multi-year deal sees the full suite of Expedia services, including flights, hotels, car hire, package holidays and dynamically packaged combos, integrated into Yahoo Travel sites in the UK, Ireland, France, Spain, Italy and Germany.
Users are able to search from a Expedia-hosted widget on the homepage as well view a special, real-time deals on other parts of the portal.
After completing a product search, users are directed to a co-branded site within Yahoo Travel to continue with further searches, product filters and bookings.
Expedia Europe director of online partner marketing, Alex Gisbertt, says the idea is to combine the strong travel content already within Yahoo Travel with a system that helps complete the plan-search-book-manage cycle for consumers.
"We have big plans which we think we can really work with this particular type of partnership with Yahoo," he adds.
The deal with Expedia ends Yahoo's long-standing agreement with Kelkoo across the majority of markets in Europe.
Kelkoo, which was bought by Yahoo in 2004 but sold again in 2008 to private equity firm Jamplant, previously had a search widget on the homepage of most Yahoo Travel sites, directing users to results on its existing price comparison service.
But perhaps the most interesting elements of the Europe deal is the switch from metasearch partner to OTA or tour operator. This is not the first time a media portal has turned from one to the other - the Telegraph newspaper site moving from Travelsupermarket to Thomas Cook being one of the more high profile.
In the US, Yahoo also toyed with metasearch but eventually closed the company it bought, FareChase.
Yahoo in the US recently extended its deal with Travelocity to include the full range of products from the OTA, ending its involvement with Orbitz for cruise and packages.