Booking.com's first foray on to the Windows 8 platform comes as no surprise given the sales it is already seeing via its mobile website and existing applications.
Last year the Priceline-owned accommodation giant claimed sales of $1 billion and that figure was surpassed in the first six months of 2012.
The service enables bookings via Windows 8 PC as well as via Microsoft's surface tablet and comes on top of iOS and Android apps.
Booking.com is not the only company betting on Windows 8, with Skyscanner also taking its flight search service live on the device.
The Skyscanner app enables list or map view as well as free text search for what it says will be a faster search experience. It also enables users to pin and track a search to their desktop via a live tile.
The UK-based metasearch company has experienced similar levels of success as its hotel OTA counterpart in Booking.com, claiming ten million downloads of its suite of mobile apps so far.