Hotelopia has been handed a contract of more than three years to furnish easyJet with hotel accommodation for its holidays arm.
Statements from the TUI-owned brand and the airline say the deal comes into effect in May and will offer customers "flexible packages comprising a wide range of flight and accommodation products".
EasyJet Holidays was unveiled in early 2011 as a "collaboration" with the Lowcost Travel Group, although Hotelopia had been providing hotel inventory to the airline prior to the holidays business being launched.
Plans are also afoot to launch six new EasyJet Holidays websites across Europe including services for Spain, the Netherlands, Germany and France.
There has been much changing of accommodation (hotel) bedfellows by low-cost carriers in recent years as they have strived to increase ancillary revenue.
This latest move attempts to position easyJet as a 'major pan-European tour operator.'
Ryanair fell out with Expedia over a white-label accommodation deal, finally settling out of court, with the carrier switching to Booking.com for a time and finally opting for metasearch service Hotelscombined.
Expedia and Aer Lingus then signed an affiliate agreement for hotels and activities on the Irish carrier's website.